Rau ntau tshaj 25 xyoo, tag nrho cov khoom noj khoom haus parenteral (TPN) tau ua lub luag haujlwm tseem ceeb hauv cov tshuaj niaj hnub. Thaum xub thawj tsim los ntawm Dudrick thiab nws pab neeg, qhov kev kho mob ntawm lub neej no tau txhim kho txoj sia nyob tau zoo rau cov neeg mob plab hnyuv, tshwj xeeb yog cov neeg mob plab hnyuv. Kev kho kom tsis tu ncua hauv catheter thev naus laus zis thiab cov tshuab nqus dej, ua ke nrog kev nkag siab tob rau hauv cov txheej txheem metabolic, tau tso cai rau kev tsim khoom noj khoom haus customized raws li tus neeg mob xav tau. Niaj hnub no, TPN yog ib qho tseem ceeb ntawm kev xaiv kho mob, nrog rau cov ntawv thov kev kho mob kom meej meej thiab cov ntaub ntawv muaj kev ruaj ntseg zoo. Ntawm lawv,TPN tasua los ntawm EVA cov ntaub ntawv tau dhau los ua cov kev ntim ntim cov kev daws teeb meem rau kev kho mob thiab khoom noj khoom haus hauv tsev vim lawv cov biocompatibility zoo heev, tshuaj lom neeg ruaj khov thiab kev nyab xeeb mus ntev. Kev hloov mus rau kev tswj hwm hauv tsev tau txhim kho nws txoj kev ua tau zoo, txo cov nqi tsev kho mob thaum tswj xyuas kev ua tau zoo. Cov kws tshawb fawb tam sim no tab tom tshawb nrhiav cov peev txheej tshiab siv rau TPN, suav nrog nws lub luag haujlwm hauv kev tswj cov mob ntev xws li atherosclerosis.
Ua ntej pib TPN, kev ntsuas kev noj haus kom zoo yog qhov tseem ceeb rau kev kho kom zoo. Cov kev ntsuas tseem ceeb suav nrog kev tshuaj xyuas tus neeg mob cov keeb kwm kho mob kom poob ceeb thawj (10% lossis ntau dua), cov leeg tsis muaj zog, thiab edema. Kev kuaj lub cev yuav tsum tsom mus rau kev ntsuas anthropometric, tshwj xeeb tshaj yog triceps skinfold thickness, uas muab kev pom zoo rau cov roj reserves. Kev soj ntsuam hauv chav kuaj feem ntau suav nrog cov qib albumin thiab hloov pauv cov ntshav, siv dav siv cov cim ntawm cov protein ntau, txawm hais tias kev kuaj tshwj xeeb ntau dua li cov protein uas retinol-binding yuav muab cov ntaub ntawv ntxiv thaum muaj. Kev tiv thaiv kab mob tuaj yeem raug soj ntsuam los ntawm tag nrho cov lymphocyte suav thiab ncua sijhawm kuaj tawv nqaij nrog cov antigens xws li PPD lossis Candida.
Ib qho cuab yeej tshwj xeeb uas muaj txiaj ntsig zoo tshaj plaws yog Prognostic Nutritional Index (PNI), uas sib txuas ntau qhov tsis sib xws rau hauv ib qho kev pheej hmoo:
PNI(%) = 158 - 16.6(serum albumin hauv g/dL) - 0.78(triceps skinfold in mm) - 0.20(transferrin in mg/dL) - 5.8(hypersensitivity score).
Cov neeg mob uas muaj PNI qis dua 40% feem ntau muaj kev pheej hmoo tsawg ntawm cov teeb meem, thaum cov qhab nia 50% lossis siab dua ntsib qhov kev pheej hmoo tuag ntau ntawm kwv yees li 33%. Qhov kev ntsuam xyuas dav dav no pab cov kws kho mob txiav txim siab txog thaum twg yuav pib TPN thiab yuav ua li cas los saib xyuas nws cov txiaj ntsig, thaum kawg txhim kho kev saib xyuas neeg mob hauv ob qho tib si mob thiab mob ntev. Kev sib koom ua ke ntawm kev txhawb nqa kev noj zaub mov zoo nrog cov txheej txheem kev soj ntsuam nruj tseem yog lub hauv paus ntawm kev coj noj coj ua niaj hnub no.
Raws li kev txhawb nqa tseem ceeb rau kev kho TPN, peb lub tuam txhab muab cov khoom zoo EVA TPN hnab. Cov khoom lag luam nruj me ntsis ua raws li cov qauv thoob ntiaj teb, tau dhau FDA thiab CE daim ntawv pov thawj, thiab tau lees paub dav hauv ntau lub khw thoob ntiaj teb, muab kev nyab xeeb thiab txhim khu kev qha rau kev kho mob thiab kev noj zaub mov hauv tsev.
Post lub sij hawm: Aug-04-2025